Janumet XR is a slow-release tablet for diet and exercise therapy to improve high blood glucose control in type 2 diabetes mellitus patients. This drug contains sitagliptin and metformin. Sitagliptin works by increasing the body’s incretin, incretin helps control blood glucose by increasing the release of insulin after meals and decreasing the amount of glucose produced in the liver. Metformin works by helping the body produce insulin naturally and reduce glucose in the liver which is absorbed by the intestine. In the use of this drug must be in accordance with the doctor’s instructions.